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    Fbll1 fibrillarin-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363563, updated on 11-Apr-2024

    Summary

    Official Symbol
    Fbll1provided by RGD
    Official Full Name
    fibrillarin-like 1provided by RGD
    Primary source
    RGD:1562841
    See related
    Ensembl:ENSRNOG00000015303 AllianceGenome:RGD:1562841
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562841
    Summary
    Predicted to enable RNA binding activity; histone-glutamine methyltransferase activity; and rRNA methyltransferase activity. Predicted to be involved in box C/D RNA 3'-end processing; histone glutamine methylation; and rRNA methylation. Predicted to act upstream of or within blastocyst hatching. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be part of box C/D RNP complex and small-subunit processome. Predicted to be active in Cajal body and nucleolus. Orthologous to human FBLL1 (fibrillarin like 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    10q12
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (20762716..20764359, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (20258656..20260299, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (20620957..20622600, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene slit guidance ligand 3 Neighboring gene uncharacterized LOC120095247 Neighboring gene microRNA 103a-1 Neighboring gene pantothenate kinase 3 Neighboring gene arginyl-tRNA synthetase 1 Neighboring gene uncharacterized LOC134480662 Neighboring gene WW and C2 domain containing 1

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables histone H2AQ104 methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables rRNA methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within blastocyst hatching ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in box C/D sno(s)RNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in rRNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in Cajal body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of box C/D methylation guide snoRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in fibrillar center IEA
    Inferred from Electronic Annotation
    more info
     
    located_in fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1
    NP_001102294.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108824.1NP_001102294.1  rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1

      See identical proteins and their annotated locations for NP_001102294.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      A6HDI9, D3ZVA5
      Related
      ENSRNOP00000020554.6, ENSRNOT00000020554.8
      Conserved Domains (1) summary
      PTZ00146
      Location:81321
      PTZ00146; fibrillarin; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      20762716..20764359 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)